Gather your ingredients.

Preheat your oven to 400 and line a baking sheet with parchment paper.

Heat olive oil in a medium skillet over medium and sauté yellow onion, mushrooms, and 1/4 tsp of salt until soft, about 5 minutes.

In a small bowl, combine the milk, egg, 2 Tbsp of ketchup, and the Worcestershire sauce.

In a separate large bowl, combine the cooked onions and mushrooms, ground turkey, panko breadcrumbs, 1/4 tsp garlic powder, 1/4 tsp black pepper, and 1/2 tsp salt.

Slowly pour the wet ingredient mix into the large bowl and mix well with a fork or your hands, being careful not to overmix.

Shape the meat mixture into a loaf and place it onto the lined baking sheet. The loaf should be about 4 inches wide, 8 inches long, and 2 inches tall.

In a small bowl, combine 3 Tbsp ketchup and the BBQ sauce and spread evenly on top of the loaf.

Bake in a preheated oven for 40-45 minutes or until the internal temperature reaches 170. Allow meatloaf to cool for 5-10 minutes, and then slice to serve and enjoy!